> ## Documentation Index
> Fetch the complete documentation index at: https://proto.evodesign.org/docs/llms.txt
> Use this file to discover all available pages before exploring further.

# Change Log

> New tools and recent development across the Proto language and tools layers

Proto is organized in two layers. The **language** contains the optimization engine together
with its constraints, generators, and optimizers. The **tools** layer contains the
bioinformatics models that the language invokes. The chart below records weekly commit activity
in both layers. Hovering a week shows the commit counts for that week, along with any commit
from it that carries a write-up in the timeline below.

<div id="changelog-chart" class="changelog-chart" />

## New Tools

<div class="changelog-tools">
  <a class="changelog-tool-card" href="/docs/tools/structure-prediction/opendde">
    <img noZoom class="changelog-tool-art" src="https://proto-bio.github.io/proto-assets/images/tool/opendde/carousel.png" alt="" loading="lazy" />

    <span class="changelog-tool-body">
      <span class="changelog-tool-date">July 24, 2026</span>
      <span class="changelog-tool-name">OpenDDE</span>
      <span class="changelog-tool-desc">All-atom co-folding for complexes of proteins, DNA, RNA, ligands, and ions.</span>
    </span>
  </a>

  <a class="changelog-tool-card" href="/docs/tools/sequence-scoring/parade">
    <img noZoom class="changelog-tool-art" src="https://proto-bio.github.io/proto-assets/images/tool/parade/carousel.png" alt="" loading="lazy" />

    <span class="changelog-tool-body">
      <span class="changelog-tool-date">July 23, 2026</span>
      <span class="changelog-tool-name">PARADE</span>
      <span class="changelog-tool-desc">Cell-type-specific UTR activity and 3' UTR mRNA stability prediction.</span>
    </span>
  </a>

  <a class="changelog-tool-card" href="/docs/tools/structure-scoring/metal3d">
    <img noZoom class="changelog-tool-art" src="https://proto-bio.github.io/proto-assets/images/tool/metal3d/carousel.png" alt="" loading="lazy" />

    <span class="changelog-tool-body">
      <span class="changelog-tool-date">June 25, 2026</span>
      <span class="changelog-tool-name">Metal3D</span>
      <span class="changelog-tool-desc">Zinc-binding site prediction and coordinates from a protein structure.</span>
    </span>
  </a>
</div>

## Commit Timeline

<div id="changelog-commits" class="changelog-commits" />

<div class="changelog-commit-notes">
  <div data-sha="c47268d4" data-title="Modal deployment for the tools layer">
    <Update label="August 3, 2026" description="Tools layer">
      <img noZoom className="block dark:hidden changelog-note-logo" src="https://mintcdn.com/bio-pro/yHRl3H3qWK3eifOJ/assets/images/logos/modal-logo.png?fit=max&auto=format&n=yHRl3H3qWK3eifOJ&q=85&s=f746cf67b930b1fda296e4d72099d526" alt="Modal" width="800" height="150" data-path="assets/images/logos/modal-logo.png" />

      <img noZoom className="hidden dark:block changelog-note-logo" src="https://mintcdn.com/bio-pro/yHRl3H3qWK3eifOJ/assets/images/logos/modal-logo-dark.png?fit=max&auto=format&n=yHRl3H3qWK3eifOJ&q=85&s=354a888f77afb5e764b193b24f8adb17" alt="Modal" width="800" height="150" data-path="assets/images/logos/modal-logo-dark.png" />

      The tools layer gained a deployment layer for the whole catalog. 54 applications serve 99 tools
      on [Modal](https://modal.com).
    </Update>
  </div>

  <div data-sha="f6564d5" data-title="OpenDDE added to structure prediction" data-date="2026-07-24" data-layer="tools">
    OpenDDE was added to the structure prediction category.
  </div>
</div>

## Contribute

The tool catalog is extended through contributions. To add a tool, fork the repository and open
a pull request; we will assist with the integration.

<CardGroup cols={2}>
  <Card title="Add a tool" icon="git-pull-request" href="https://github.com/evo-design/proto-tools/blob/main/CONTRIBUTING.md">
    Fork proto-tools and open a pull request. CONTRIBUTING.md documents the layout and conventions.
  </Card>

  <Card title="Contact us" icon="mail" href="https://forms.gle/8PiYPDiuf3YfNxxH8">
    Describe what you would like to see in Proto and how we can assist.
  </Card>
</CardGroup>
