> ## Documentation Index > Fetch the complete documentation index at: https://proto.evodesign.org/docs/llms.txt > Use this file to discover all available pages before exploring further. # Binder Design > End-to-end de novo binder and antibody design pipelines Design protein binders and antibodies against a target structure. These end-to-end pipelines generate a candidate backbone, design a sequence for it, and score the resulting interface, repeating the loop to produce binders that engage the target. The outputs are computational candidates intended for downstream evaluation and experimental testing. * **Input:** a target structure, optionally with specified hotspot or epitope residues. * **Output:** candidate binder or antibody structures, each with interface confidence and quality scores.

Arc Institute