> ## Documentation Index
> Fetch the complete documentation index at: https://proto.evodesign.org/docs/llms.txt
> Use this file to discover all available pages before exploring further.

# RNA Splicing

> Predict splice sites and tissue-specific splicing patterns

Predict RNA splice sites and the effect of sequence variants on splicing. These tools
estimate per-position donor and acceptor probabilities, some with tissue-specific
resolution, for analyzing alternative splicing and isoform usage. They help anticipate how
an edit changes which splice sites are used.

* **Input:** an RNA or DNA sequence, or a sequence variant.
* **Output:** per-position splice donor and acceptor probabilities, or a predicted change in splicing for a variant.

<div class="tool-catalog-grid">
  <a href="/docs/tools/rna-splicing/pangolin" class="tool-catalog-card">
    <img noZoom class="card-art" src="https://proto-bio.github.io/proto-assets/images/tool/pangolin/carousel.png" alt="" loading="lazy" />
  </a>

  <a href="/docs/tools/rna-splicing/splice-transformer" class="tool-catalog-card">
    <img noZoom class="card-art" src="https://proto-bio.github.io/proto-assets/images/tool/splice_transformer/carousel.png" alt="" loading="lazy" />
  </a>

  <a href="/docs/tools/rna-splicing/spliceai" class="tool-catalog-card">
    <img noZoom class="card-art" src="https://proto-bio.github.io/proto-assets/images/tool/spliceai/carousel.png" alt="" loading="lazy" />
  </a>
</div>