License: AlphaGenome uses Apache-2.0 for code and Custom (AlphaGenome Terms of Use) for model weights and has restrictions around commercial use and may require explicit attribution when utilized. Model weights are gated and require accepting the provider’s terms and authenticating with a HuggingFace token. Please refer to the code license and model weights license for full terms.
This constraint is open source. Any third-party models, product names, or trademarks referenced are the property of their respective owners, and Proto is not affiliated with them.
evo-design/proto-language/proto_language/constraint/rna_splicing/alphagenome_splice_junction.pyConstraint contributors
adititm
Score splice-junction support at configured donor/acceptor positions.
adititmAPI Reference
Configuration for AlphaGenome splice-junction scoring.
string
required
Genomic context sequence for cassette integration.
string
required
Left flanking cassette context.
string
required
Right flanking cassette context.
List[string]
required
AlphaGenome ontology term(s) to score.
integer
required
0-based donor position in left_flank + intron_core + right_flank.
integer
required
0-based acceptor position in left_flank + intron_core + right_flank.
enum
default:"max"
‘max’ rewards junction support; ‘min’ penalizes it.Options:
max, minenum
default:"positive"
Track strand subset to aggregate.Options:
positive, negative, allstring
default:"all_folds"
AlphaGenome model version.
enum
default:"human"
Organism for AlphaGenome prediction.Options:
human, mousestring
default:"cuda"
Device for AlphaGenome prediction.
integer
default:"3600"
Timeout in seconds for AlphaGenome prediction.
Usage
python