- Input: a DNA sequence, or a sequence variant to evaluate.
- Output: predicted functional and regulatory activity (such as expression or accessibility), or a variant’s effect on it.
Sequence Scoring
Sequence Scoring
Predict functional effects from genomic sequences
Predict functional genomic readouts directly from DNA sequence, including gene expression,
chromatin accessibility, transcription initiation, and regulatory activity. These tools
estimate how a sequence behaves and how variants change that behavior, at resolutions
ranging from individual regulatory elements to long genomic windows.
Google DeepMind
Calico
USC
Broad Institute
The Jackson Laboratory
Yale University
UCSF
Autosome.org
UT Southwestern
St. Jude
NCBI