Prototypes
Explore read-only starter programs below, or sign up to create and run your own.
Starter examples
Simple “Hello World” programs for understanding the design language.
Toy DNA optimization
Designs a 100 bp DNA sequence with balanced GC content and short homopolymers.
Protein diversification
Diversifies the GB1 domain and filters for sequence quality and predicted structure confidence.
σ70 promoter tuning
Tunes a bacterial promoter and terminator around a fixed reporter context.
Protein design examples
Protein sequence design programs with structure-aware objectives.
Protein monomer hallucination
Uses the Protein Hunter method to alternate structure prediction with inverse folding for monomer design.
Symmetric homotrimer design
Designs three tied protein chains and scores whether they form a confident symmetric assembly.
De novo nanobody design
Uses the Germinal method to redesign a VHH binder against PD-L1 with gradient-guided and MCMC optimization stages.
DNA design examples
Regulatory and noncoding DNA programs for controlling sequence-level function.
K562 enhancer specificity
Uses Malinois and gradient optimization to design a 200 bp regulatory DNA insert with high K562 activity and low HepG2/SK-N-SH activity.
Intron splicing design
Optimizes a variable intron inside fixed flanking sequence for splice-site and sequence-quality constraints.
Chromatin Morse code design
Uses Evo 2 and beam search to design synthetic DNA with a target chromatin-accessibility signal pattern.
System design examples
Programs coordinating multiple genes, constructs, or linked regulatory parts.
CRISPR-Cas generation
Samples CRISPR-Cas operons and performs Cas9, CRISPR-array, and tracrRNA identification.
Signaling pathway design
Diversifies a linked β-adrenergic signaling pathway from receptor activation through CREB transcriptional readout.